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Moreover, NMN supplement can alleviate aluminum-induced bone injuries via suppression of the thioredoxin-interacting protein (TXNIP)NLRP3 inflammasome pathway (Liang et al., 2019)

Consistent with perturbed glutathione metabolism, CLP mice exhibited significant downregulation of the Nrf2/HO-1 antioxidant axis: reduced Nrf2, a master transcriptional regulator of antioxidant genes, and its target HO-1 were reduced, indicating impaired upstream antioxidant regulation

Using a socio-technical lens (Geels, 2005), we analyze three medium-sized municipalities in a peripheral European region undergoing service transformation